- Aquaettes
- Book Club
- Butler High Theatre
- Club de Francais
- Cross Trainers
- Fellowship of Christian Athletes
- Engineering Club
- Environmental Club
- F.I.T.E Club
- Future Business Leaders of America
- German Club
- Good Will Ambassador's Club
- Junior Classical League
- Marching Band
- Magnet
- Mock Trial
- Music Dept
- National Honor Society
- Orchestra
- Pennsylvania Junior Academy of Science
- Photography Club
- Random Acts of Kindness
- Skyliner (School Newspaper)
- Smart Lab
- Spanish Club
- Stand Tall
- Student Council
- Ukelele Club
- Video Club
